Category: How is Mifeprex given?

How is Mifeprex given?

How is Mifeprex given?, Before receiving this medicine, you must read a Mifeprex Medication Guide. Then, you must sign a Patient Agreement form stating that you understand the risks and benefits of using this medicine.

Complete treatment to end the pregnancy will require at least 2 visits to your doctor.

  • At the first visit (Day 1) you will be given a Mifeprex tablet. You will also be given or prescribed 4 misoprostol tablets.
  • In 24 to 48 hours, you will take 4 misoprostol tablets at one time. For treatment to be effective, you must take misoprostol 24 to 48 hours after you take Mifeprex.
  • You will likely have fairly heavy vaginal bleeding while your uterus is passing the pregnancy.
  • At the second visit (Days 7 to 14 after you took Mifeprex), your doctor will check your uterus to make sure the pregnancy has completely ended.
  • If you take a second dose of misoprostol, you should have a follow-up visit 7 days later.

How do abortion pills work?

Abortion pills cause the embryo to detach from the uterus, cutting off essential nutrients and oxygen carried by the blood. This also triggers the evacuation of the embryo remnants through the vagina, which often appears as a heavy period. Also, abortion medications block the hormone progesterone, which continues a pregnancy.

Mifeprex

Generic name: mifepristone (Mifeprex) (MIF e PRIS tone)
Brand name: Mifeprex
Drug class: Progesterone receptor modulators, Uterotonic agents

What is mifepristone (Mifeprex)?

Mifeprex blocks the actions of a hormone needed to maintain a pregnancy.

Mifepristone is used to end an early pregnancy that is not further along than 70 days (10 weeks) after the first day of your last menstrual period. Mifeprex is used together with another medicine called misoprostol (Cytotec).

Mifepristone is available only from a certified healthcare provider under a special program.

Mifeprex must not be in an attempt to end pregnancy beyond 10 weeks

This medication guide provides information about the Mifeprex brand of mifepristone.

Mifeprex may also be used for purposes not listed in this medication guide.

Before taking this medicine

Do not use Mifeprex or misoprostol if you do not intend to end your pregnancy. Mifeprex may cause birth defects in an unborn baby if the treatment procedure does not fully terminate the pregnancy. You may need surgery to end the pregnancy completely.

Treatment with Mifeprex and misoprostol requires at least 2 visits to your doctor. Do not use Mifeprex if you cannot attend all required follow-up visits.

You should not take Mifeprex or misoprostol if you are allergic to either medicine or if:

  • It has been more than 70 days (10 weeks) since your last menstrual period began;
  • You have a pregnancy outside the uterus (ectopic pregnancy);
  • You have problems with your adrenal glands (chronic adrenal failure);
  • Have porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system);
  • Also, you have a condition for which you use a blood thinner such as warfarin (Coumadin, Jantoven);
  • And you have a condition for which you have been taking steroid medicine for a long period of time; or
  • You are allergic to prostaglandins.

To make sure Mifeprex is safe for you, tell your doctor if you have:

  • a history of uterine rupture or uterine scar; or
  • kidney disease.

Mifeprex can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is Mifeprex given?

Before receiving this medicine, you must read a Mifeprex Medication Guide. Then, you must sign a Patient Agreement form stating that you understand the risks and benefits of using this medicine.

Complete treatment to end the pregnancy will require at least 2 visits to your doctor.

  • In 24 to 48 hours, you will take 4 misoprostol tablets at one time. For treatment to be effective, you must take misoprostol 24 to 48 hours after you take Mifeprex.
  • Misoprostol can cause cramps, nausea, diarrhea, and other side effects. Your doctor may give you medicine to treat or prevent these side effects.
  • Your uterus should begin to pass the pregnancy within 2 to 24 hours after taking misoprostol. But Be sure you are in a place where you will be ready for this to happen. You will likely have fairly heavy vaginal bleeding while your uterus is passing the pregnancy.
  • At the second visit (Days 7 to 14 after you took Mifeprex), your doctor will check your uterus to make sure the pregnancy has completely ended.
  •  If you take a second dose of misoprostol, you should have a follow-up visit 7 days later.

Cramping and bleeding are signs that this medicine is working properly. But sometimes you can have cramping and bleeding and still be pregnant. Only your doctor can confirm whether your pregnancy has completely ended. Do not miss any of your follow-up visits.

Bleeding and spotting are normal side effects of Mifeprex and misoprostol. It is possible to continue bleeding for up to 30 days. Bleeding may be heavier than a normal heavy period, and you may also pass blood clots and tissue.

What happens if I miss a dose?

Since Mifeprex is used as a single dose, it does not have a daily dosing schedule.

Call your doctor for instructions if you miss any follow-up appointments.

What happens if I overdose?

Since Mifeprex is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after taking Mifeprex?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity.

Grapefruit and grapefruit juice can make it harder for your body to metabolize Mifeprex. Avoid the use of grapefruit products shortly before or after taking Mifeprex.

Mifeprex side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a fever higher than 100.4 degrees F (38 degrees C) lasting longer than 4 hours;
  • a general ill feeling or fast heartbeats;
  • severe pelvic pain or tenderness;
  • severe or ongoing nausea, vomiting, diarrhoea, weakness; or
  • no vaginal bleeding at all after taking Mifeprex.

Common side effects may include:

  • heavy vaginal bleeding for 2 days;
  • light vaginal bleeding or spotting for up to 16 days;
  • fever, chills, weakness;
  • dizziness; or
  • nausea, vomiting, diarrhea.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. But you may report side effects to the FDA at 1-800-FDA-1088.

Mifeprex side effects (more detail)

What other drugs will affect Mifeprex?

Tell your doctor about all your current medicines, especially:

  • medication to treat hepatitis or HIV;
  • an antibiotic or antifungal medication;
  • heart or blood pressure medication;
  • seizure medication; or
  • tuberculosis medication.
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